Y. BRUN - Mechanism of bacterial surface attachment

Y. BRUN - Mechanism of bacterial surface attachment and biophysical analysis of a strong bacterial adhesion

20 mai 2015

Salle séminaire FR AIB

Yves V. Brun (Department of Biology, Indiana University), actuellement en séjour sabbatique au LMGM à Toulouse, présente un séminaire sur le thème "Mechanism of bacterial surface attachment and biophysical analysis of a strong bacterial adhesion", dans le cadre du cycle des séminaires invités coordonné par la FR AIB.

Abstract

The attachment of bacteria to surfaces provides advantages such as increasing nutrient access and resistance to environmental stress. Attachment begins with a reversible phase, often mediated by surface structures such as flagella and pili, followed by a transition to irreversible attachment, typically mediated by polysaccharides. The presentation will focus on stimulatory and inhibitory mechanisms of cell attachment and biofilm formation. I will describe how the interplay between pili and flagellum rotation of Caulobacter crescentus cells stimulates the rapid transition between reversible and polysaccharide-mediated irreversible attachment by stimulating the biosynthesis of the holdfast adhesive polysaccharide. I will also describe a biophysical analysis of the impressive adhesive properties of the holdfast.

References

Li, G., Brown, P.B., J.X. Tang, Zhu, J., Quardokus, E.M., Fuqua, C., and Y.V. Brun.  2012.  Surface contact stimulates the just-in-time deployment of bacterial adhesins.  Molecular Microbiology, 83:41-51.

C. Berne, X. Ma, N. Licata, B. Neves, S. Setayeshgar, Y.V. Brun, and B. Dragnea. 2013. Physiochemical Properties of Caulobacter crescentus Holdfast: a Localized Bacterial Adhesive. Journal of Physical Chemistry, 117: 10492-503.

En savoir plus sur Yves Brun :

Contact :

Matthieu.Arlat@toulouse.inra.fr

Contact: changeMe@inrae.fr